Home (2R,3S)-2,3-Bis(benzoyloxy)-4-methoxy-4-oxobutanoic acid CAS Number 115061-55-7 Category Intermediate Final Application HIV Proteases Molecular Formula C19H16O7 Molecular Weight 356.32 A chiral, dibenzoylated tartrate-derived building block used in the synthesis of HIV protease inhibitor APIs, where its defined (2R,3S) stereocenters are carried through to set the stereochemistry of the peptidomimetic core of the final drug. Your name […]

Home 2-(2-Fluoro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS Number 1599432-41-3 Category Intermediate Final Application Sotorasib Molecular Formula C13H18BFO3 Molecular Weight 252.09 A fluoro-methoxyphenyl boronic ester (pinacol boronate) used as a key Suzuki-coupling partner in the synthesis of Sotorasib, a targeted KRAS G12C inhibitor for non-small cell lung cancer, contributing the fluorinated aryl fragment of the final molecule Your name Your […]

Home 4-Hydroxycarbazole CAS Number 52602-39-8 Category Intermediate Final Application Carvedilol Molecular Formula C12H9NO Molecular Weight 183.21 4-Hydroxycarbazole is the tricyclic carbazole core used to build Carvedilol, a non-selective beta-blocker with alpha-1 blocking activity used in hypertension and heart failure. Its phenolic hydroxyl is alkylated with an epoxide fragment to install carvedilol’s ether-linked aminopropanol side chain. […]

Home 2,3,5-Triiodobenzoic Acid CAS Number 88-82-4 Category Fine Chemical / Intermediate Final Application X-ray Contrast Agents Molecular Formula C7H3I3O2 Molecular Weight 471.81 A tri-iodinated benzoic acid used as the aromatic core for iodinated X-ray contrast media APIs (e.g., diatrizoic acid and related agents), where the high iodine content provides the radiopacity needed for radiographic and […]

Home Rac-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine CAS Number 79617-96-2 Category Intermediate Final Application Sertraline Molecular Formula C17H17Cl2N Molecular Weight 310.23 The racemic amine intermediate formed by reductive amination of the dichlorophenyl-tetralone. It is resolved to the desired (1S,4S) enantiomer and salified to produce Sertraline HCl, the final antidepressant API. Your name Your email Your message (optional)

Home 4-(3,4-Dichlorophenyl)-1-tetralone CAS Number 79560-19-3 Category Intermediate Final Application Sertraline Molecular Formula C16H12Cl2O Molecular Weight 291.17 A dichlorophenyl-substituted tetralone that serves as the core aromatic tetralin building block for Sertraline, an SSRI antidepressant; it is subsequently reductively aminated to install the methylamine group that defines sertraline’s active stereochemistry. Your name Your email Your message (optional)

Home 1-Ethoxycarbonyl-3-phenylpropyl]-L-alanine (ECPP A) CAS Number 82717-96-2 Category Intermediate Final Application Enalapril & Ramipril Molecular Formula C14H19NO4 Molecular Weight 265.31 ECPP-A is the key chiral side-chain intermediate shared by the ACE-inhibitor antihypertensives Enalapril and Ramipril, supplying the ethyl-ester-protected phenylpropyl-alanine fragment that is coupled to each API’s respective bicyclic amino-acid core. Your name Your email Your […]

Home 2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose CAS Number 4132-28-9 Category Intermediate Final Application Empagliflozin Molecular Formula C34H36O6 Molecular Weight 552.65 A fully benzyl-protected glucose derivative used as the sugar-donor fragment in the synthesis of Empagliflozin and related SGLT2-inhibitor “gliflozin” APIs, where it is coupled to the aryl core via a C-glycosylation reaction before the benzyl protecting groups are removed. […]

Home 5-Pentylresorcinol (Olivetol) CAS Number 500-66-3 Category Intermediate Final Application Cannabidiol Molecular Formula C11H16O2 Molecular Weight 180.24 A monoterpene alcohol related to limonene, used together with olivetol as one of the two coupling partners in the classical acid-catalyzed synthesis of Cannabidiol (CBD), supplying the terpenoid half of the CBD molecule. Your name Your email Your […]

Home p-Mentha-2,8-dien-1-ol CAS Number 22771-44-4 Category Intermediate Final Application Cannabidiol Molecular Formula C10H16O Molecular Weight 152.23 A monoterpene alcohol related to limonene, used together with olivetol as one of the two coupling partners in the classical acid-catalyzed synthesis of Cannabidiol (CBD), supplying the terpenoid half of the CBD molecule. Your name Your email Your message […]